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TP 003

Cat. No. M7420

All AbMole products are for research use only, cannot be used for human consumption.

TP 003 Structure

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Quality Control & Documentation
Biological Activity

TP 003 is a functionally selective GABAA receptor (α3 subtype) partial agonist. Exhibits affinity for the benzodiazepine binding site on human GABAA receptors. Potentiates the GABA (α3 subtype) response selectively with high efficacy. Produces anxiolytic-like effects in rodent behavioral models of anxiety.

Chemical Information
Molecular Weight 407.39
Formula C23H16F3N3O
CAS Number 628690-75-5
Solubility (25°C) DMSO 40.74 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Testa, et al. J Pharmacol Exp Ther. Pharmacological characterization of the uroselective alpha-1 antagonist Rec 15/2739 (SB 216469): Role of the alpha-1L adrenoceptor in tissue selectivity, part II.

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Keywords: TP 003 supplier, inhibitors, activators

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