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TMS

Cat. No. M7416

All AbMole products are for research use only, cannot be used for human consumption.

TMS Structure
Synonym:

(E)-2,3',4,5'-tetramethoxystilbene

Size Price Availability Quantity
5mg USD 60 In stock
10mg USD 95 In stock
50mg USD 350 In stock
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Quality Control & Documentation
Biological Activity

TMS is a potent, selective and competitive inhibitor of cytochrome P450 1B1, an enzyme overexpressed in certain tumors (IC50 = 6 nM). 50- and 520-fold selective over P450 1A1 and 1A2 respectively. Inhibits cancer cell growth in vitro.

Chemical Information
Molecular Weight 300.35
Formula C18H20O4
CAS Number 24144-92-1
Form Solid
Solubility (25°C) DMSO 30.04 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Kennett, et al. Neuropharmacology. BW 723C86, a 5-HT2B receptor agonist, causes hyperphagia and reduced grooming in rats.

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Keywords: TMS, (E)-2,3',4,5'-tetramethoxystilbene supplier, Cytochrome P450 (e.g. CYP17), inhibitors, activators

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