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TMP920 

Cat. No. M28386

All AbMole products are for research use only, cannot be used for human consumption.

TMP920  Structure

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Quality Control & Documentation
Biological Activity

TMP920 is a highly potent and selective RORγt antagonist. TMP920 inhibits RORγt binding to the SRC1 peptide with an IC50 of 0.03 μM.

Chemical Information
Molecular Weight 454.56
Formula C29H30N2O3
CAS Number 1421837-45-7
Form Solid
Solubility (25°C) DMSO 62.5 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Sheng Xiao, et al. Immunity. Small-molecule RORγt antagonists inhibit T helper 17 cell transcriptional network by divergent mechanisms

[2] Jacob S Lee, et al. Immunity. The emerging landscape of RORγt biology

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  Catalog
Abmole Inhibitor Catalog




Keywords: TMP920  supplier, ROR, inhibitors, activators

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