Free shipping on all orders over $ 500

TM38837

Cat. No. M10718

All AbMole products are for research use only, cannot be used for human consumption.

TM38837 Structure
Size Price Availability Quantity
5mg USD 150 In stock
10mg USD 200 In stock
25mg USD 400 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

TM38837 is an orally active, peripherally restricted cannabinoid receptor type 1 (CB1) receptor antagonist.TM38837 has limited penetration into the brain and minimizes or prevents CNS adverse effects.

Chemical Information
Molecular Weight 617.51
Formula C30H25Cl2F3N4OS
CAS Number 1253641-65-4
Form Solid
Solubility (25°C) DMSO ≥ 20 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Vincenzo Micale, et al. Front Pharmacol. The Cannabinoid CB1 Antagonist TM38837 With Limited Penetrance to the Brain Shows Reduced Fear-Promoting Effects in Mice

[2] Akihiro Takano, et al. Synapse. Low brain CB1 receptor occupancy by a second generation CB1 receptor antagonist TM38837 in comparison with rimonabant in nonhuman primates: a PET study

[3] Robert J Chorvat. Bioorg Med Chem Lett. Peripherally restricted CB1 receptor blockers

[4] Linda E Klumpers, et al. Br J Clin Pharmacol. Peripheral selectivity of the novel cannabinoid receptor antagonist TM38837 in healthy subjects

Related Cannabinoid Products
Org 27569

Org 27569 is a potent and selective allosteric modulator of the cannabinoid CB1 receptor.

AM1241

AM1241 is a cannabinoid CB2 receptor selective agonist.

CP 945598 hydrochloride

CP 945598 hydrochloride is a selective and high affinity CB1 antagonist (Ki values are 0.7 and 0.12 nM in binding and functional assays respectively).

AM-2201

AM-2201 is a potent synthetic cannabinoid (CB) with Ki values of 1.0 and 2.6 nM for the CB1 and CB2 receptors, respectively.

AM251

AM251 block the inhibitory effects of endocannabinoids and synthetic cannabinoid agonists on transmitter release through an action at presynaptic cannabinoid 1 receptors in brain.

  Catalog
Abmole Inhibitor Catalog




Keywords: TM38837 supplier, Cannabinoid, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.