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TLX agonist 1 

Cat. No. M30975

All AbMole products are for research use only, cannot be used for human consumption.

TLX agonist 1  Structure

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Quality Control & Documentation
Biological Activity

TLX agonist 1 (ccrp2) is an orphan nuclear receptor tailless (TLX, NR2E1) modulator (EC50=1μM; Kd= 650 nM). TLX agonist 1 potentiates TLX transcriptional repressive activity.

Chemical Information
Molecular Weight 374.48
Formula C23H26N4O
CAS Number 958323-31-4
Form Solid
Solubility (25°C) DMSO 62.5 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Jiayi Zhou, et al. J Immunother Cancer. Orphan nuclear receptor TLX promotes immunosuppression via its transcriptional activation of PD-L1 in glioma

[2] Ximena Corso-Díaz, et al. BMC Genomics. Co-activator candidate interactions for orphan nuclear receptor NR2E1

[3] Pablo Juárez, et al. Behav Brain Res. Serotonin₂A/C receptors mediate the aggressive phenotype of TLX gene knockout mice

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Keywords: TLX agonist 1  supplier, inhibitors, activators

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