All AbMole products are for research use only, cannot be used for human consumption.
C29 is a Toll-like receptor 2 (TLR2) inhibitor. C29 blocked HTLR2/1 and HTLR2/6 with IC50 values of 19.7 and 37.6 μM, respectively.
Int J Mol Sci. 2026 Jan 07;27.
Asiatic Acid Attenuates Salmonella typhimurium-Induced Neuroinflammation and Neuronal Damage by Inhibiting the TLR2/Notch and NF-κB Pathway in
TLR2-IN-C29 purchased from AbMole
J Leukoc Biol. 2024 May 15;qiae114.
Treponema pallidum recombinant protein Tp0768 enhances the ability of HUVECs to promote neutrophil chemotaxis through TLR2/ER stress signaling pathway
TLR2-IN-C29 purchased from AbMole
Int Immunopharmacol. 2023 Jun 23;121:110547.
Toll-like receptor 2 deficiency alleviates acute pancreatitis by inactivating the NF-κB/NLRP3 pathway
TLR2-IN-C29 purchased from AbMole
| Molecular Weight | 285.29 |
| Formula | C16H15NO4 |
| CAS Number | 363600-92-4 |
| Solubility (25°C) | DMSO: ≥ 25 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related TLR Products |
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Vesatolimod (GS-9620) is an effective, selective, oral toll-like receptor 7 (TLR7) agonist with an EC50 value of 291 nM. |
| Atractylenolide I
Atractylenolide I is a sesquiterpene obtained from the roots of Atractylenolide. Atractylenolide I has neuroprotective, anti-allergic, anti-inflammatory and anticancer activities. Atractylenolide I is an antagonist of TLR4 and can also reduce the phosphorylation of JAK2 and STAT3 in A375 cells. |
| Schaftoside
Schaftoside is a flavonoid found in a variety of Chinese herbs such as Eleusine indica. Schaftoside inhibited TLR4 and Myd88 expression. Schaftoside also reduced Drp1 expression and phosphorylation, and reduced mitochondrial division. |
| Procyanidin-B1
Procyanidin B1 is a polyphenolic flavonoid that exists in common fruits and can bind to TLR4/MD-2 complex, showing anti-inflammatory activity. |
| Polygalasaponin-F
Polygalasaponin F is an oleanane type triterpenoid saponin extracted from Polygala Japonica, which can reduce the release of inflammatory cytokine tumor necrosis factor α (TNFa). Polygalasaponin F reduces the secretion of neuroinflammatory cytokines by regulating the TLR4-PI3K/ Akt-NF-KB signaling pathway. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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