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Timapiprant sodium

Cat. No. M14046

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Timapiprant sodium Structure
Synonym:

OC000459 sodium

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Quality Control & Documentation
Biological Activity

Timapiprant (OC000459) sodium is a potent, selective, and orally active D prostanoid receptor 2 (DP2, also known as CRTH2) antagonist. Timapiprant sodium (OC000459 sodium) potently displaces [3H] PGD2 from human recombinant DP2 (Ki=13 nM), rat recombinant DP2 (Ki=3 nM), and human native DP2 (Ki=4 nM). Timapiprant sodium (OC000459 sodium) inhibits mast cell activation of Th2 lymphocytes and eosinophils.

Chemical Information
Molecular Weight 370.35
Formula C21H16FN2NaO2
CAS Number 950688-14-9
Solubility (25°C) DMSO 90 mg/mL
Storage 2-8°C, sealed
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Keywords: Timapiprant sodium, OC000459 sodium supplier, Prostaglandin Receptor, inhibitors, activators

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