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Tilavonemab

Cat. No. M24912

All AbMole products are for research use only, cannot be used for human consumption.

Tilavonemab Structure
Synonym:

ABBV-8E12; C2N-8E12

Size Price Availability Quantity
100ug USD 145 In stock
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Quality Control & Documentation
Biological Activity

Tilavonemab (ABBV-8E12) is a humanised anti-tau antibody that binds amino acids 25-30 near the N-terminal end of the tau protein. Tilavonemab blocks the ability of human and mouse neurons to take up tau aggregates and reduces brain atrophy. Tilavonemab can be used in the study of Alzheimer's disease.

Chemical Information
CAS Number 2096513-89-0
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Hana Florian, et al. Brain. Tilavonemab in early Alzheimer's disease: results from a phase 2, randomized, double-blind study

[2] Günter U Höglinger. Lancet Neurol. Neuropathology of progressive supranuclear palsy after treatment with tilavonemab - Author's reply

[3] Shunsuke Koga, et al. Lancet Neurol. Neuropathology of progressive supranuclear palsy after treatment with tilavonemab

[4] Günter U Höglinger, et al. Lancet Neurol. Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial

[5] Miguel Vaz, et al. Eur J Pharmacol. Alzheimer's disease: Recent treatment strategies

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Keywords: Tilavonemab, ABBV-8E12; C2N-8E12 supplier, Microtubule, inhibitors, activators

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