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Ticagrelor is the first reversibly binding oral P2Y12 receptor antagonist with Ki of 2 nM respectively.
Drug Des Devel Ther. 2025 Nov 04;19:9825-9844.
P2Y12R Blockade Attenuates LPS-Induced Acute Lung Injury Associated with Suppression of Inflammasome-Mediated Pyroptotic Signaling.
Ticagrelor purchased from AbMole
| Molecular Weight | 522.57 |
| Formula | C23H28F2N6O4S |
| CAS Number | 274693-27-5 |
| Solubility (25°C) | DMSO 90 mg/mL |
| Storage | -20°C, protect from light, sealed |
[1] George Dangas, et al. Ticagrelor With or Without Aspirin After Complex PCI
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