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Thyroid hormone receptor antagonist (1-850) is a competitive, selective and high-affinity thyroid hormone receptor (TR) antagonist with an IC50 of 1.5 μM for antagonizing the effect of T3 on TR. Thyroid hormone receptor antagonist (1-850) blocks T3-mediated interaction of TRα and TRβ with nuclear receptor coactivator.
| Molecular Weight | 463.41 |
| Formula | C21H20F3N5O4 |
| CAS Number | 251310-57-3 |
| Form | Crystalline Solid |
| Storage | Store at -20°C |
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