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Thiocolchicoside is a potent competitive γ-aminobutyric acid type A (GABAA) receptor antagonist and glycine receptor agonist with muscle relaxant, anti-inflammatory, and analgesic activity. Thiocolchicoside has also been found to suppress nuclear factor kappa B ligand (RANKL) activation of NF-KB resulting in suppression of osteoclastogenesis.
| Molecular Weight | 563.62 |
| Formula | C27H33NO10S |
| CAS Number | 602-41-5 |
| Solubility (25°C) | Water: 10 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[2] Srgio M Martinho, et al. Visual Hallucinations After Treatment With Thiocolchicoside
[3] No authors listed. Prescrire Int. Thiocolchicoside: review of adverse effects
[4] Cumali Efe, et al. Thiocolchicoside-induced liver injury
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