All AbMole products are for research use only, cannot be used for human consumption.
Tenofovir hydrate is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B. Tenofovir shows cytotoxic effects on cell viability in HK-2 cells, with IC50 values of 9.21 and 2.77 μM at 48 and 72 h in MTT assay, respectively. Tenofovir diminishes ATP levels in HK-2 cells. Tenofovir (3.0 to 28.8 μM) increases oxidative stress and protein carbonylation in HK-2 cells. Furthermore, Tenofovir induces apoptosis in HK-2 cells, and that apoptosis is induced via mitochondrial damage.
| Molecular Weight | 305.23 |
| Formula | C9H16N5O5P |
| CAS Number | 206184-49-8 |
| Solubility (25°C) | DMSO 5 mg/mL |
| Storage | 2-8°C, sealed |
[2] James Riddell 4th, et al. JAMA. HIV Preexposure Prophylaxis: A Review
| Related HIV Protease Products |
|---|
| Atazanavir Sulfate
Atazanavir sulfate (BMS-232632, Reyataz) is an azapeptide inhibitor of HIV-1 protease. Atazanavir sulfate is a substrate and inhibitor of CYP3A4, and an inhibitor and inducer of P-glycoprotein (P-gp). Atazanavir sulfate is also a SARS-CoV 3CLpro inhibitor with an IC50 of 3.49 μM. |
| Bevirimat
Bevirimat (BVM), also known as PA-457 or MPC-4326, is a novel Human Immunodeficiency Virus type 1 (HIV-1) maturation inhibitor. |
| Lopinavir
Lopinavir (ABT-378) is a potent protease inhibitor. |
| Ritonavir
Ritonavir is an HIV protease inhibitor used in the study of HIV infection and AIDS. Ritonavir (ABT 538) |
| Delavirdine mesylate
Delavirdine mesylate is a nonnucleoside reverse transcriptase inhibitor of human immunodeficiency virus type 1 (HIV-1). |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
