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Tenofovir alafenamide fumarate

Cat. No. M20784

All AbMole products are for research use only, cannot be used for human consumption.

Tenofovir alafenamide fumarate Structure
Synonym:

TAF fumarate, GS-7340 fumarate

Size Price Availability Quantity
5mg USD 55 In stock
10mg USD 75 In stock
25mg USD 130 In stock
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Biological Activity

Tenofovir alafenamide (TAF, GS-7340) fumarate is a precursor compound of Tenofovir and a novel nucleotide reverse transcriptase inhibitor for use in studies related to HIV-1 infection.

Chemical Information
Molecular Weight 592.54
Formula C25H33N6O9P
CAS Number 379270-38-9
Solubility (25°C) DMSO 100 mg/mL
Water 10 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] William A Lee, et al. Antivir Ther. Tenofovir alafenamide fumarate

[2] Shahin Lockman, et al. Lancet. Efficacy and safety of dolutegravir with emtricitabine and tenofovir alafenamide fumarate or tenofovir disoproxil fumarate, and efavirenz, emtricitabine, and tenofovir disoproxil fumarate HIV antiretroviral therapy regimens started in pregnancy (IMPAACT 2䲧皬Ỵ皭㧀皫羹癆甿ᅸڳƌڳĀ�癈嶁癄Ѐ瑖噔

[3] Kenneth H Mayer, et al. Lancet. Emtricitabine and tenofovir alafenamide vs emtricitabine and tenofovir disoproxil fumarate for HIV pre-exposure prophylaxis (DISCOVER): primary results from a randomised, double-blind, multicentre, active-controlled, phase 3, non-inferiority trial

[4] Kosh Agarwal, et al. J Hepatol. 96 weeks treatment of tenofovir alafenamide vs. tenofovir disoproxil fumarate for hepatitis B virus infection

[5] Blandine Aloy, et al. AIDS Rev. Is Tenofovir Alafenamide Safer than Tenofovir Disoproxil Fumarate for the Kidneys?

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Keywords: Tenofovir alafenamide fumarate, TAF fumarate, GS-7340 fumarate supplier, Reverse Transcriptase, inhibitors, activators

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