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TCB2 is a high affinity 5-HT2A receptor agonist (Ki values are 0.73 and 0.75 nM for rat and human receptors respectively). TCB2 potently stimulates IP3 accumulation in NIH3T3 cells stably expressing rat 5-HT2A receptors (EC50 = 36 nM). TCB2 induces head twitches and hypothermia in mice following i.p. adminitration.
| Molecular Weight | 353.05 |
| Formula | C11H14BrNO2.HBr |
| CAS Number | 912342-28-0 |
| Solubility (25°C) | DMSO 65 mg/mL Water 20 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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