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TC13172 

Cat. No. M29198

All AbMole products are for research use only, cannot be used for human consumption.

TC13172  Structure
Size Price Availability Quantity
1mg USD 160 In stock
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Quality Control & Documentation
Biological Activity

TC13172 is an inhibitor of MLKL and necroptosis that acts on HT-29 cells with an EC50 value of 2 nM.

Chemical Information
Molecular Weight 388.4
Formula C17H16N4O5S
CAS Number 2093393-05-4
Form Solid
Solubility (25°C) DMSO 25 mg/mL (ultrasonic)
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bo Cui, et al. J Med Chem. Discovery of a New Class of Uracil Derivatives as Potential Mixed Lineage Kinase Domain-like Protein (MLKL) Inhibitors

[2] Y Ji, et al. Biomolecules. Reconstitution of Human Necrosome Interactions in Saccharomyces cerevisiae

[3] Bo Yan, et al. Chem Commun (Camb). Discovery of a new class of highly potent necroptosis inhibitors targeting the mixed lineage kinase domain-like protein

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  Catalog
Abmole Inhibitor Catalog




Keywords: TC13172  supplier, Necroptosis, inhibitors, activators

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