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TC-I 2014

Cat. No. M7376

All AbMole products are for research use only, cannot be used for human consumption.

TC-I 2014 Structure
Size Price Availability Quantity
1mg USD 100 In stock
5mg USD 165 In stock
10mg USD 265 In stock
25mg USD 480 In stock
50mg USD 650 In stock
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Quality Control & Documentation
Biological Activity

TC-I 2014 is a potent TRPM8 antagonist (IC50 values are 0.8, 3.0 and 4.4 nM for canine, human and rat channels respectively). Exhibits antiallodynic properties in pain models in vivo.

Chemical Information
Molecular Weight 467.41
Formula C23H19F6N3O
CAS Number 1221349-53-6
Solubility (25°C) DMSO 46.74 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Minucci, et al. Proc Natl Acad Sci USA. Retinoid X receptor-selective ligands produce malformations in Xenopus embryos.

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Keywords: TC-I 2014 supplier, inhibitors, activators

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