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TC-I 2000 is a tRPM8 channel blocker. Inhibits icilin-induced TRPM8 channel activation in rTRPM8-expressing CHO cells (IC50 = 53 nM).
| Molecular Weight | 414.4 |
| Formula | C23H18F4N2O |
| CAS Number | 1159996-20-9 |
| Solubility (25°C) | DMSO 41.44 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[1] Beindl, et al. Mol Pharmacol. Inhibition of receptor/G protein coupling by suramin analogues.
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