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TC-F 2

Cat. No. M7369

All AbMole products are for research use only, cannot be used for human consumption.

TC-F 2 Structure

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Quality Control & Documentation
Biological Activity

TC-F 2 is a potent, reversible inhibitor of fatty acid amide hydrolase (FAAH) (IC50 values are 28 and 100 nM for human and rat FAAH respectively). Noncovalent inhibitor; displays selectivity for FAAH over cannabinoid-related targets (IC50 > 20 μM for CB1, CB2 and TRPV1). Active in vivo.

Chemical Information
Molecular Weight 439.51
Formula C26H25N5O2
CAS Number 1304778-15-1
Solubility (25°C) DMSO 43.95 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Gierse, et al. J Biol Chem. A single amino acid difference between cyclooxygenase-1 (COX-1) and -2 (COX-2) reverses the selectivity of COX-2 specific inhibitors.

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Keywords: TC-F 2 supplier, inhibitors, activators

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