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TB 21007 is a gABAA receptor inverse agonist selective for the α5-subtype (Ki values are 1.6, 16, 20 and 20 nM for α5, α2, α1 and α3 subtypes respectively). Brain penetrant; enhances cognitive performance in rats in the delayed matching-to-place morris water maze test following i.p. administration.
| Molecular Weight | 339.5 |
| Formula | C15H17NO2S3 |
| CAS Number | 207306-50-1 |
| Solubility (25°C) | DMSO 33.95 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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