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TAT-GluN2BCTM is a membrane-permeable DAPK1-targeting peptide that targets active DAPK1 to the lysosome for degradation and protects neurons from oxidative stress and NMDAR-mediated excitotoxicity by knocking down DAPK1. TAT-GluN2BCTM is a membrane-permeable DAPK1-targeting peptide that targets active DAPK1 to lysosomes for degradation, and also protects neurons from oxidative stress and NMDAR-mediated excitotoxicity by knocking down DAPK1.
| Molecular Weight | 5135.91 |
| Formula | C224H374N86O54 |
| CAS Number | 1587742-50-4 |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related DAPK Products |
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| TC-DAPK 6
TC-DAPK 6 is a potent, ATP-competitive, and highly selective DAPK inhibitor (IC50=69 and 225 nM against DAPK1 and DAPK3, respectively, with 10 μM ATP). |
| HS38
HS38 is a potent, selective, ATP-competitive inhibitor of DAPK1 and ZIPK (DAPK3) with Kd values of 300 nM and 280 nM, respectively.In addition, HS38 is an inhibitor of PIM3 with an IC50 value of 200 nM.HS38 has been used in the study of smooth muscle-related diseases. |
| DRAK2-IN-1
DRAK2-IN-1 is a potent, selective, ATP-competitive DRAK2 inhibitor with IC50 and Ki values of 3 nM and 0.26 nM, respectively.In addition, DRAK2-IN-1 also inhibits DRAK1 (IC50=51 nM). |
| DAPK Substrate Peptide TFA
DAPK Substrate Peptide TFA is a synthetic peptide substrate for death-associated protein kinase (DAPK) with a Km of 9 μM.Sequence: Lys-Lys-Arg-Pro-Gln-Arg-Arg-Tyr-Ser-Asn-Val-Phe |
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