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Tarenflurbil

Cat. No. M14524

All AbMole products are for research use only, cannot be used for human consumption.

Tarenflurbil Structure
Synonym:

(R)-Flurbiprofen; MPC7869

Size Price Availability Quantity
50mg USD 60 In stock
100mg USD 90 In stock
250mg USD 140 In stock
500mg USD 210 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

Tarenflurbil ((R)-Flurbiprofen) is the R-enantiomer of the racemate NSAID Flurbiprofen, Tarenflurbil ((R)-Flurbiprofen) inhibits the binding of [3H]9-cis-RA to RXRα LBD with IC50 of 75 μM. Tarenflurbil can be used for Alzheimer's disease research.

Chemical Information
Molecular Weight 244.26
CAS Number 51543-40-9
Solubility (25°C) DMSO ≥ 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Mary Sano. Tarenflurbil: mechanisms and myths

[2] Bruno Vellas. Tarenflurbil for Alzheimer's disease: a "shot on goal" that missed

[3] Xu Zhao, et al. Tarenflurbil protection from cytotoxicity is associated with an upregulation of neurotrophins

[4] Paul S Aisen. Tarenflurbil: a shot on goal

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Adapalene

Adapalene is a third-generation topical retinoid, it is a potent RAR agonist, with AC50 values of 2.3 nM, 9.3 nM, and 22 nM for RARβ, RARγ, RARα, respectively. Adapalene also inhibits the enzymatic activity of GOT1 in a non-competitive manner. Adapalene is also an MST1 agonist.

Tamibarotene

Tamibarotene is a synthetic retinoic acid receptor (RAR) agonist with high specificity for RARα and RARβ over RARγ.

TTNPB

TTNPB (Arotinoid Acid) is a potent RAR agonist, and inhibits binding of [3H]tRA with IC50 of 5.1 nM, 4.5 nM, and 9.3 nM for human RARα, β, and γ, respectively.

Fenretinide

Fenretinide (4-HPR) is a synthetic retinoid deriverative. Fenretinide is shown to exhibit binding to the retinoic acid receptors (RAR) at concentrations necessary to induce cell death.

  Catalog
Abmole Inhibitor Catalog




Keywords: Tarenflurbil, (R)-Flurbiprofen; MPC7869 supplier, RAR/RXR, inhibitors, activators

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