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Taniborbactam hydrochloride (VNRX-5133 hydrochloride) is a reversible and selective boronic acid-containing pan-spectrum β-lactamase inhibitor with IC50s of 8-530 nM. Taniborbactam hydrochloride has IC50s of 30 nM, 32 nM, 42 nM, 20 nM for KPC-2, AmpC, OXA-48, and VIM-2. Taniborbactam hydrochloride is against Gram-negative bacteria.
| Molecular Weight | 462.18 |
| Formula | C19H30BCl2N3O5 |
| CAS Number | 2244235-49-0 |
| Form | Solid |
| Solubility (25°C) | DMSO 200 mg/mL (ultrasonic) Water 33.33 mg/mL (ultrasonic) |
| Storage | -20°C, protect from light, sealed |
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