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Tanezumab

Cat. No. M25263

All AbMole products are for research use only, cannot be used for human consumption.

Tanezumab Structure
Synonym:

RN-624; PF 4383119

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Quality Control & Documentation
Biological Activity

Tanezumab (RN-624) is a humanized anti-NGF mAb with high affinity and specificity. Tanezumab blocks NGF binding to its receptors, p75 and TrkA, in the peripheral nervous system. Tanezumab can be used in studies of acute and chronic pain such as osteoarthritis, knee and neuralgia, as well as post-herpetic neuralgia.

Chemical Information
CAS Number 880266-57-9
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Farva R Gondal, et al. Drugs Today (Barc). Tanezumab for the treatment of osteoarthritis pain

[2] Shin-Ichi Konno, et al. Pain Manag. Tanezumab for chronic low back pain: a long-term, randomized, celecoxib-controlled Japanese Phase III safety study

[3] Marc C Hochberg, et al. Arthritis Rheumatol. Long-Term Safety and Efficacy of Subcutaneous Tanezumab Versus Nonsteroidal Antiinflammatory Drυgs for Hip or Knee Osteoarthritis: A Randomized Trial

[4] Michael P Webb, et al. Ther Clin Risk Manag. Tanezumab: a selective humanized mAb for chronic lower back pain

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Keywords: Tanezumab, RN-624; PF 4383119 supplier, inhibitors, activators

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