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Tamoxifen Citrate (ICI 46474)

Cat. No. M2280

All AbMole products are for research use only, cannot be used for human consumption.

Tamoxifen Citrate (ICI 46474) Structure
Synonym:

ICI 46474; Istubal; Nolvadex

Size Price Availability Quantity
Free Sample (0.5-1 mg)  USD 0 In stock
10mM*1mL in DMSO USD 55 In stock
100mg USD 40 In stock
500mg USD 60 In stock
1g USD 80 In stock
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Quality Control & Documentation
Biological Activity

Tamoxifen Citrate (Nolvadex) is an estrogen receptor antagonist with an IC50 of 31 μM for the MCF-7 cells. In some tissues such as the endometrium, it behaves as an agonist, hence tamoxifen may be characterized as a mixed agonist/antagonist.

Chemical Information
Molecular Weight 563.64
Formula C26H29NO.C6H8O7
CAS Number 54965-24-1
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Turgut Karaca, et al. Int J Surg. Effects of tamoxifen citrate on postoperative intra-abdominal adhesion in a rat model

[2] V Hug, et al. J Clin Oncol. Tamoxifen-citrate counteracts the antitumor effects of cytotoxic drugs in vitro

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Keywords: Tamoxifen Citrate (ICI 46474), ICI 46474; Istubal; Nolvadex supplier, Estrogen Receptor, inhibitors, activators

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