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Talsaclidine

Cat. No. M8799

All AbMole products are for research use only, cannot be used for human consumption.

Talsaclidine Structure

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Quality Control & Documentation
Biological Activity

Talsaclidine is a M1 selective muscarinic receptor agonist. Concentration-dependently, talsaclidine increases the release of APPs and dose-dependently. Talsaclidine decreases Aβ formation and decreases cerebrospinal fluid Aβ in AD patients.

Chemical Information
Molecular Weight 165.23
Formula C10H15NO
CAS Number 147025-53-4
Solubility (25°C) DMSO: ≥5 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Atish Kumar Sahoo, et al. Features and outcomes of drugs for combination therapy as multi-targets strategy to combat Alzheimer's disease

[2] Alvin V Terry Jr, et al. Memory-related task performance by aged rhesus monkeys administered the muscarinic M(1)-preferring agonist, talsaclidine

[3] A Walland, et al. Central activation of the sympathetic nervous system including the adrenals in anaesthetized guinea pigs by the muscarinic agonist talsaclidine

[4] A Walland, et al. In vivo consequences of M1-receptor activation by talsaclidine

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