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Talacotuzumab-MMAE is an antibody-drug conjugate (ADC) targeting IL-3Ra / CD123. Talacotuzumab (JNJ 56022473; CSL 362) is an IgG1-type fully humanized, CD123-neutralizing monoclonal antibody.
Immobilized human IL 3RA at 2 ug/mL can bind Talacotuzumab-MMAE, the EC50 is 0.1648 ug/mL.
Subtype IgG1
Molecular weight 145 kDa
Endotoxin <1 EU/mg
| Form | Solution |
| Solubility (25°C) | For powder, reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. |
| Storage | Store at ≤ -20℃ for 24 months. Avoid repeated freeze-thaw cycles. |
| Related Antibody-Drug Conjugates (ADCs) Products |
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