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Tabalumab

Cat. No. M24555

All AbMole products are for research use only, cannot be used for human consumption.

Tabalumab Structure
Synonym:

LY2127399

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Quality Control & Documentation
Biological Activity

Tabalumab (LY2127399) is a humanised anti-BAFF (B-cell activating factor) monoclonal antibody (IgG4 type) with neutralising activity against membrane bound and soluble BAFF. Tabalumab can be used in studies of autoimmune diseases such as rheumatoid arthritis, renal failure and systemic lupus erythematosus.

Chemical Information
CAS Number 1143503-67-6
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Yaxin Jiang, et al. J Mol Model. Distinct binding mode of BAFF antagonist antibodies belimumab and tabalumab, analyzed by computer simulation

[2] Ayse Bag-Ozbek, et al. Ther Clin Risk Manag. Emerging B-Cell Therapies in Systemic Lupus Erythematosus

[3] David Isenberg. Ann Rheum Dis. Further thoughts about the ILLUMINATE studies of tabalumab in SLE

[4] Fabien B Vincent, et al. Cytokine Growth Factor Rev. The BAFF/APRIL system: emerging functions beyond B cell biology and autoimmunity

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Keywords: Tabalumab, LY2127399 supplier, TNF Receptor, inhibitors, activators

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