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T0467 is a potential PINK1-Parkin signaling activator that activates mitochondrial parkin translocation in a PINK1-dependent manner, but does not induce mitochondrial aggregation of PINK1 in dopaminergic neurons. It can be used in the study of Parkinson's disease and related disorders.
| Molecular Weight | 441.49 |
| Formula | C24H26F3N5 |
| CAS Number | 859518-94-8 |
| Form | Solid |
| Solubility (25°C) | DMSO 33.33 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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