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T 98475

Cat. No. M7345

All AbMole products are for research use only, cannot be used for human consumption.

T 98475 Structure

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Quality Control & Documentation
Biological Activity

T 98475 is a potent, orally active and non-peptide gonadotropin-releasing hormone (GnRH, LHRH) receptor antagonist (IC50 values are 0.2, 4.0 and 60 nM for human, monkey and rat GnRH receptors respectively). Inhibits LH release in vitro (IC50 = 100 nM) and reduces plasma LH concentration in castrated male cynomolgus monkeys.

Chemical Information
Molecular Weight 657.77
Formula C37H37F2N3O4S
CAS Number 199119-18-1
Solubility (25°C) DMSO 32.89 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Haynes, et al. TiPS. Endothelin; progress in pharmacology and physiology.

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Keywords: T 98475 supplier, inhibitors, activators

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