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T 5601640

Cat. No. M7344

All AbMole products are for research use only, cannot be used for human consumption.

T 5601640 Structure
Synonym:

T5601640

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Quality Control & Documentation
Biological Activity

T 5601640 is a selective LIM kinase 2 (LIMK2) inhibitor; inhibits cofilin phosphorylation in cells that overexpress LIMK2 but not LIMK1. Attenuates the growth of several cancer cell lines. Reduces phospho-cofilin levels and Panc-1 tumor size in a mouse xenograft model.

Chemical Information
Molecular Weight 389.33
Formula C19H14F3N3O3
CAS Number 924473-59-6
Solubility (25°C) DMSO 19.47 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Minamimura, et al. Antimicrob Agents Chemother. In vitro antibacterial activity and beta-lactamase stability of CP-70,429 a new penem antibiotic.

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Keywords: T 5601640, T5601640 supplier, inhibitors, activators

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