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Texas Red (Sulforhodamine 101) is an amphoteric rhodamine red fluorescent dye (excitation/emission: 586/605 nm). Texas Red is used extensively for investigating neuronal morphology and acts as acell type-selective fluorescent marker of astrocytes bothin vivoand in slice preparations
Furthermore, this fluorophore is used as an activity-dependent dye for monitoring regulated exocytosis. Alternate studies suggest that Sulforhodamine 101 can increase intrinsic neuronal excitability and long-lasting increases in evoked EPSCs in CA1 pyramidal neurons in hippocampal slices. Texas Red (Sulforhodamine 101) enhances evoked synaptic N-methyl D-aspartate receptor (NMDAR) currents which can be blocked by the antagonist, AP-5.
| Molecular Weight | 606.71 |
| Formula | C31H30N2O7S2 |
| CAS Number | 60311-02-6 |
| Form | Solid |
| Solubility (25°C) | DMSO 40 mg/mL Water 7 mg/mL |
| Storage | -20°C, protect from light |
[1] Hulsmann S, et al. Front Cell Neurosci. Limitations of Sulforhodamine 101 for Brain Imaging.
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