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Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic acid. Sulfadimethoxine blocks the synthesis of dihydrofolic acid by inhibiting the enzyme dihydropteroate synthase. The sorption coefficients (K(d)) obtained for the sulfonamides investigated were quite low (from 0.20 to 381.17 mL g(-1) for sulfadimethoxine and from 0.39 to 35.09 mL g(-1) for sulfaguanidine), which indicated that these substances are highly mobile and have the potential to run off into surface waters and/or infiltrate ground water.
| Molecular Weight | 310.33 |
| Formula | C12H14N4O4S |
| CAS Number | 122-11-2 |
| Solubility (25°C) | DMSO ≥ 56 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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