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Strictosidinic acid is an orally active glycoside indole monoterpene alkaloid, which inhibits precursor enzymes of 5-HT biosynthesis and reduces the 5-HT levels.
Strictosidinic acid (10 mg/kg; i.p.) causes a 63.4% reduction in 5-HT levels and a 67.4% reduction in DOPAC values in male Wistar rats, weighing 200-250 g. Strictosidinic acid has peripheral analgesic and antipyretic activities in mice.
| Molecular Weight | 516.54 |
| Formula | C26H32N2O9 |
| CAS Number | 150148-81-5 |
| Form | Solid |
| Solubility (25°C) | DMSO 100 mg/mL (ultrasonic) |
| Storage | 4°C, sealed |
[4] Rosane de P Castro, et al. Acta Crystallogr C. Absolute configuration of strictosidinic acid
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