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STING agonist-31

Cat. No. M42058

All AbMole products are for research use only, cannot be used for human consumption.

STING agonist-31 Structure

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Quality Control & Documentation
Biological Activity

STING agonist-31 is a STING agonist, with EC50 values of 0.24 and 39.51 μM for h-STING and m-STING.

Chemical Information
Molecular Weight 873.96
Formula C43H51N15O6
CAS Number 2719001-44-0
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] J Lane Wilson et al. Prim Care. Venom Hypersensitivity

[2] A Aulanier et al. J Fr Ophtalmol. Corneal hornet sting

[3] Angel N Desai. JAMA. Dog Bites

[4] Preben Aavitsland. Tidsskr Nor Laegeforen. Under the skin

[5] Fernando J Bula-Rudas et al. Pediatr Rev. Human and Animal Bites

Related STING Products
Vadimezan

Vadimezan (DMXAA; ASA-404) acts as a tumor vascular disrupting agent (tumor-VDA), is also a murine agonist of the stimulator of interferon genes (STING) and also a potent inducer of type I IFNs and other cytokines.

G10

G10 is a activator of STING-dependent signaling.

3′3′-cGAMP

3',3'-cGAMP is an endogenous second messenger in metazoans and triggers interferon production in response to cytosolic DNA. 3',3'-cGAMP activates stimulator of interferon genes (STING), which activates a signaling cascade leading to the production of type I interferons and other immune mediators.

diABZI (tautomerism)

diABZI (STING agonist 1; Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively.

C-176

C-176 is a potent, selective and blood-brain barrier permeable inhibitor of STING. C-176 covalently targets transmembrane cysteine residue 91 and thereby blocking activation-induced palmitoylation of STING.

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Keywords: STING agonist-31 supplier, STING, inhibitors, activators

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