All AbMole products are for research use only, cannot be used for human consumption.
ST2825 significantly inhibited the proliferation of and promoted the apoptosis of HCC cells. Moreover, ST2825 significantly decreased bcl-2 expression, increased cleaved caspase-3 expression (P < 0.05), and reduced p65 nuclear expression (P < 0.05) in a dose-dependent manner.
In vivo, animals are administered orally with the appropriate vehicles or ST2825 at doses ranging from 50 to 200 mg/kg, 5 min prior to i.p. injection with 20 μg/kg IL-1β. ST2825 exertes a significant inhibition of IL-1β-stimulated production of IL-6 at 100 and 200 mg/kg.
Int J Biol Macromol. 2025 Jun 20; .
Immunoregulatory function and anticancer effects of Polygonatum sibiricum polysaccharides against hepatic carcinoma via macrophage phenotype modulation
ST2825 purchased from AbMole
| Molecular Weight | 591.51 |
| Formula | C27H28Cl2N4O5S |
| CAS Number | 894787-30-5 |
| Form | Solid |
| Solubility (25°C) | DMSO 10 mM |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related Immunology/Inflammation Products |
|---|
| Laquinimod
Laquinimod (ABR-215062) is a new orally active immunoregulator effectively inhibits development and relapses of experimental autoimmune encephalomyelitis. |
| Cyclosporine A
Cyclosporine A (CsA，Cyclosporin A) is an immunosuppressant that binds to cyclophilin and inhibits calcineurin with an IC50 of 7 nM. Cyclosporine A [CsA] binds to the cyclophilin 18 (Cyp18)-CsA complex. the Cyp18-CsA complex recruits calcium-regulated neurophosphatase (CaN), leading to the blocking of cytokine gene transcription in activated T cells. CsA is a highly specific inhibitor of T-cell activation. |
| Pimecrolimus
Pimecrolimus is an immunomodulating agent used in the treatment of atopic dermatitis. |
| Meloxicam
Meloxicam (Mobic) is a nonsteroidal anti-inflammatory agent with analgesic and fever reducer effects. |
| Mycophenolic acid
Mycophenolic acid is an immunosuppressant agent used to prevent rejection in organ transplantation. |
All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.
