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SSTC3

Cat. No. M45281

All AbMole products are for research use only, cannot be used for human consumption.

SSTC3 Structure
Size Price Availability Quantity
5mg USD 270 In stock
10mg USD 425 In stock
25mg USD 640 In stock
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Quality Control & Documentation
Biological Activity

SSTC3 is a Casein kinase 1α (CK1α) agonist (Kd = 32 nM) and inhibits WNT signaling (EC50 = 30 nM).

Chemical Information
Molecular Weight 518.53
Formula C23H17F3N4O3S2
CAS Number 1242422-09-8
Form Solid
Solubility (25°C) DMSO >100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Bin Li, et al. Sci Signal. Differential abundance of CK1α provides selectivity for pharmacological CK1α activators to target WNT-dependent tumors

[2] Xiaomin Liu, et al. Stem Cell Res Ther. Nicotinamide improves in vitro lens regeneration in a mouse capsular bag model

[3] Mingyu Pan, et al. Autophagy. CSNK1A1/CK1α suppresses autoimmunity by restraining the CGAS-STING1 signaling

[4] Jezabel Rodriguez-Blanco, et al. Clin Cancer Res. A CK1α Activator Penetrates the Brain and Shows Efficacy Against Drug-resistant Metastatic Medulloblastoma

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Keywords: SSTC3 supplier, Casein Kinase, inhibitors, activators

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