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SRPKIN-1 is a covalent and irreversible SRPK1/2 inhibitor with IC50s of 35.6 and 98 nM, respectively. Anti-angiogenesis effect.
| Molecular Weight | 472.53 |
| Formula | C27H21FN2O3S |
| CAS Number | 2089226-94-6 |
| Form | Solid |
| Solubility (25°C) | DMSO ≥ 110 mg/mL |
| Storage | -20°C, dry, sealed |
| Related SRPK Products |
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| SRPIN340
SRPIN340 is a selective SRPK inhibitor with Ki of 0.89 μM for SRPK1, showing no significant inhibitory activity against more than 140 other kinases. |
| SPHINX31
SPHINX31 is a potent inhibitor of serine/arginine-rich protein kinase 1 (SRPK1) with IC50 of 5.9 nM. SPHINX31 inhibits phosphorylation of serine/arginine-rich splicing factor 1 (SRSF1). |
| WAY-652848
WAY-652848 is a selective inhibitor of SRPK1 with an IC50 value of 0.58 μM.WAY-652848 effectively reduces choroidal neovascularization (CNV) in vivo, and can be used in the study of age-related macular degeneration. |
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