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SQLE-IN-1 is a squalene cyclooxygenase (SQLE) inhibitor and inhibits the proliferation and migration of Huh7 cells. In addition, SQLE-IN-1 inhibits cellular cholesterol production, increases PTEN expression, and inhibits PI3K and AKT expression.
| Molecular Weight | 481.52 |
| Formula | C24H21F2N5O2S |
| CAS Number | 1019169-83-5 |
| Form | Solid |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
| Related PTEN Products |
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SF1670 is a pTPN2 and PTEN inhibitor. |
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| bpV(HOpic) potassium salt
BpV(HOpic) is a protein tyrosine phosphatases (PTPs) and a potent PTEN inhibitor with IC50 of 14 nM. |
| Ginkgolic acid 17:1
Ginkgolic acid 17:1, a natural product isolated from Ginkgo biloba, inhibits constitutive and inducible STAT3 activation by inducing PTEN and SHP-1 tyrosine phosphatases. In addition, Ginkgolic acid C17:1 has anticancer activity. |
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