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SQ109

Cat. No. M8492

All AbMole products are for research use only, cannot be used for human consumption.

SQ109 Structure
Synonym:

NSC 722041

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Quality Control & Documentation
Biological Activity

SQ109 is an anti-tuberculosis compound used in the study of multi-drug resistant tuberculosis (MDR-TB). SQ109 inhibits the activity of MmpL3, a mycoacid transporter required by M. tuberculosis to incorporate mycoacid into its cell wall.

Chemical Information
Molecular Weight 330.55
Formula C22H38N2
CAS Number 502487-67-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Satish R Malwal, et al. Structure, In Vivo Detection, and Antibacterial Activity of Metabolites of SQ109, an Anti-Infective Drug Candidate

[2] Oluwaseun Egbelowo, et al. Pharmacokinetics and Target Attainment of SQ109 in Plasma and Human-Like Tuberculosis Lesions in Rabbits

[3] Sergey Bukhdruker, et al. Hydroxylation of Antitubercular Drug Candidate, SQ109, by Mycobacterial Cytochrome P450

[4] Venkata M Reddy, et al. SQ109 and PNU-100480 interact to kill Mycobacterium tuberculosis in vitro

[5] No authors listed. Tuberculosis (Edinb). SQ109

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  Catalog
Abmole Inhibitor Catalog




Keywords: SQ109, NSC 722041 supplier, inhibitors, activators

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