Free shipping on all orders over $ 500

SQ109

Cat. No. M8492

All AbMole products are for research use only, cannot be used for human consumption.

SQ109 Structure
Synonym:

NSC 722041

Price and Availability

For this product's availability, delivery time and price, please email inquiry@abmole.com directly or click the "Inquiry Now" button below.


Quality Control & Documentation
Biological Activity

SQ109 is an anti-tuberculosis compound used in the study of multi-drug resistant tuberculosis (MDR-TB). SQ109 inhibits the activity of MmpL3, a mycoacid transporter required by M. tuberculosis to incorporate mycoacid into its cell wall.

Chemical Information
Molecular Weight 330.55
Formula C22H38N2
CAS Number 502487-67-4
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Satish R Malwal, et al. Structure, In Vivo Detection, and Antibacterial Activity of Metabolites of SQ109, an Anti-Infective Drug Candidate

[2] Oluwaseun Egbelowo, et al. Pharmacokinetics and Target Attainment of SQ109 in Plasma and Human-Like Tuberculosis Lesions in Rabbits

[3] Sergey Bukhdruker, et al. Hydroxylation of Antitubercular Drug Candidate, SQ109, by Mycobacterial Cytochrome P450

[4] Venkata M Reddy, et al. SQ109 and PNU-100480 interact to kill Mycobacterium tuberculosis in vitro

[5] No authors listed. Tuberculosis (Edinb). SQ109

Related Products
Lactate calcium

Lactate calcium is an excellent calcium fortifier that works better than inorganic calcium. Lactate calcium is used as an antacid.

Coniferyl ferulate

Coniferyl ferulate is a potent glutathione S-transferase (GST) inhibitor that reverses multidrug resistance and down-regulates p-glycoprotein. Coniferyl ferulate strongly inhibited human placental glutathione S-transferase with IC50 of 0.3 μM.

NXY-059

NXY-059 is a free radical-trapping neuroprotectant that has been reported to reduce infarct size and preserve brain function in experimental models of acute ischemic stroke.

Tie2 kinase inhibitor

Tie2 kinase inhibitor is a potent, reversible, and ATP-binding site-targeting Tie2 inhibitor with an IC50 of 250 nM.

Calcium levofolinate

Calcium levofolinate is a calcium salt of folinic acid that is an adjuvant used in cancer chemotherapy.

  Catalog
Abmole Inhibitor Catalog




Keywords: SQ109, NSC 722041 supplier, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.