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Mixed NMDA agonist/antagonist at the polyamine site. Neuroprotective effects have been observed at high concentrations (1 mM), while neurotoxicity is observed at lower concentrations. It enhances agonist effectiveness at the strychnine-insensitive glycine site. Plays a role in cellular proliferation and differentiation; inhibits neuronal nitric oxide synthase (nNOS).
| Molecular Weight | 348.18 |
| Formula | C10H26N4 · 4HCl |
| CAS Number | 306-67-2 |
| Solubility (25°C) | water high purity: 100 mg/ml |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
[4] A DAMIANI, et al. X-RAY STUDY OF SPERMINE TETRAHYDROCHLORIDE
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