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Spermidine

Cat. No. M14410

All AbMole products are for research use only, cannot be used for human consumption.

Spermidine Structure
Size Price Availability Quantity
250mg USD 40 In stock
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Quality Control & Documentation
Biological Activity

Spermidine maintains cell membrane stability, increases antioxidant enzymes activities, improving photosystem II (PSII), and relevant gene expression. Spermidine significantly decreases the H2O2 and O2.- contents.

Chemical Information
Molecular Weight 145.25
CAS Number 124-20-9
Solubility (25°C) Water 100 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Xiaoyu Liu, et al. Spermidine inhibits vascular calcification in chronic kidney disease through modulation of SIRT1 signaling pathway

[2] Indrani Ghosh, et al. Spermidine, an autophagy inducer, as a therapeutic strategy in neurological disorders

[3] Jingjing Fan, et al. Spermidine as a target for cancer therapy

[4] Ting-Ting Xu, et al. Spermidine and spermine delay brain aging by inducing autophagy in SAMP8 mice

[5] Frank Madeo, et al. Spermidine in health and disease

Related Metabolite/Endogenous Metabolite Products
2'-Deoxyinosine

2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. It is a DNA damage product resulting from the impairment of DNA by reactive nitrogen species. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability.

Ribitol

Ribitol (Adonitol) is a crystalline pentose alcohol formed by the reduction of ribose.

Glycodeoxycholic Acid

Glycodeoxycholic Acid is an endogenous metabolite. Glycodeoxycholic Acid induces hepatocyte necrosis and autophagy in patients with obstructive cholestasis.

Glycolithocholic acid

Glycolithocholic acid, an endogenous metabolite, is a glycine conjugated secondary bile acid. Glycolithocholic acid can be used to study ulcerative colitis (UC), non-alcoholic steatohepatitis (NASH0) and primary sclerosing cholangitis (PSC).

4-Aminohippuric Acid

4-Aminohippuric acid is a typical substrate of organic anion transport systems. 4-Aminohippuric acid is a diagnostic agent, useful in medical tests involving the kidney, used in the measurement of renal plasma flow.

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