Free shipping on all orders over $ 500

SPDP Crosslinker

Cat. No. M10401

All AbMole products are for research use only, cannot be used for human consumption.

SPDP Crosslinker Structure
Synonym:

SPDP NHS ester; Py-ds-Prp-OSu

Size Price Availability Quantity
25mg USD 90 In stock
50mg USD 140 In stock
100mg USD 210 In stock
250mg USD 450 In stock
500mg USD 600 In stock
Free Delivery on orders over USD 500 Bulk Inquiry?

Quality Control & Documentation
Biological Activity

SPDP crosslinker, or SPDP NHS ester, is a cleavable, water insoluble, amino and thiol (sulfhydryl) reactive heterobifunctional protein crosslinker. The SPDP Crosslinker is useful in making antibody drug conjugates (ADCs).

*The compound is unstable in solutions, freshly prepared is recommended

Chemical Information
Molecular Weight 312.36
Formula C12H12N2O4S2
CAS Number 68181-17-9
Solubility (25°C) DMSO ≥ 100 mg/mL
Storage -20°C, protect from light, sealed
References

[1] Subha Karumuthil-Melethil, et al. J Immunol. Dendritic cell-directed CTLA-4 engagement during pancreatic beta cell antigen presentation delays type 1 diabetes

[2] Sune Lobedanz, et al. Proc Natl Acad Sci U S A. A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps

[3] V Singh, et al. Indian J Exp Biol. Effect of lysine residue modification of ovine luteinizing hormone by heterobifunctional crosslinking reagent SPDP on subunit-subunit association, receptor binding and biological activity

Related ADC Linker Products
6-Maleimidohexanoic acid N-hydroxysuccinimide ester

6-Maleimidohexanoic acid N-hydroxysuccinimide ester(ECMS) is a useful protective group in antibody drug conjugates.

Sulfo-NHS

Sulfo-NHS is a peptide condensing agent, can form a stable active ester intermediate, used to prepare hydrophilic active ester, for example as a protein cross-linking agent. N-Hydroxysulfosuccinimide (sodium) is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

Mc-Val-Cit-PAB

Mc-Val-Cit-PAB is a peptide linker molecule used in the synthesis of antibody-drug conjugates (ADCs).

Fmoc-Val-Cit-PAB

Fmoc-Val-Cit-PAB-OH is a cleavable useful heterobifunational linker for making Antibody-Drug-Conjugates (ADC).

Fmoc-Val-Cit-PAB-PNP

Fmoc-Val-Cit-PAB-PNP is a cleavable peptide ADC linker which used in the synthesis of antibody-drug conjugates (ADCs).

  Catalog
Abmole Inhibitor Catalog




Keywords: SPDP Crosslinker, SPDP NHS ester; Py-ds-Prp-OSu supplier, ADC Linker, inhibitors, activators

All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.



Products are for research use only. Not for human use. We do not sell to patients.
© Copyright 2010-2026 AbMole BioScience. All Rights Reserved.