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Sparteine

Cat. No. M19338

All AbMole products are for research use only, cannot be used for human consumption.

Sparteine Structure

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Quality Control & Documentation
Biological Activity

(+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons.

Chemical Information
Molecular Weight 234.38
Formula C15H26N2
CAS Number 492-08-0
Form Liquid
Solubility (25°C) Water 2.86 mg/mL (ultrasonic)
Storage 4°C, protect from light, dry, sealed
References

[1] Fridha Villalpando-Vargas, et al. Seizure. Sparteine as an anticonvulsant drug: Evidence and possible mechanism of action

[2] K VAN DONGEN, et al. Arch Int Pharmacodyn Ther. Sparteine

[3] Thomas Buttler, et al. Org Biomol Chem. A synthesis of (+/-)-sparteine

[4] U A Meyer, et al. Pharmacol Ther. The genetic polymorphism of debrisoquine/sparteine metabolism-molecular mechanisms

[5] M S Lennard. Pharmacol Toxicol. Genetic polymorphism of sparteine/debrisoquine oxidation: a reappraisal

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Keywords: Sparteine supplier, AChR/AChE, inhibitors, activators

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