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SOS1 activator 1 (Compound 64) is a potent activator of SOS1-mediated nucleotide exchange with a Kd of 44 nM. SOS1 is a guanine nucleotide exchange factor that catalyzes the exchange of GDP for GTP on RAS.
| Molecular Weight | 483.02 |
| Formula | C26H32ClFN6 |
| CAS Number | 2245237-53-8 |
| Storage | Please store the product under the recommended conditions in the Certificate of Analysis. |
[2] Ye Eun Kim, et al. Mol Cells. Neurodevelopmental Aspects of RASopathies
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