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Sophoridine

Cat. No. M13522

All AbMole products are for research use only, cannot be used for human consumption.

Sophoridine Structure
Size Price Availability Quantity
20mg USD 80 In stock
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Quality Control & Documentation
Biological Activity

Sophoridine is a quinolizidine alkaloid isolated from leafs of Leguminous plant Sophora alopecuroides.L. Sophoridine induces apoptosis. Sophoridine has the potential to be a novel, potent and selective antitumor drug candidate for pancreatic cancer with well-tolerated toxicity.

Chemical Information
Molecular Weight 248.36
CAS Number 6882-68-4
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Qi Wang, et al. Phytomedicine. Sophoridine: A review of its pharmacology, pharmacokinetics and toxicity

[2] Zhongwei Zhao, et al. J Cell Mol Med. Sophoridine suppresses lenvatinib-resistant hepatocellular carcinoma growth by inhibiting RAS/MEK/ERK axis via decreasing VEGFR2 expression

[3] Zhiyang Peng, et al. BMC Cancer. Sophoridine exerts tumor-suppressive activities via promoting ESRRG-mediated β-catenin degradation in gastric cancer

[4] Haroon Ur Rashid, et al. Bioorg Chem. Anti-cancer potential of sophoridine and its derivatives: Recent progress and future perspectives

[5] Rui Wang, et al. Mol Cancer Res. Sophoridine Inhibits Human Colorectal Cancer Progression via Targeting MAPKAPK2

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Keywords: Sophoridine supplier, Apoptosis, inhibitors, activators

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