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Sontuzumab

Cat. No. M25220

All AbMole products are for research use only, cannot be used for human consumption.

Sontuzumab Structure
Synonym:

AS1402; huHMFG-1

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Quality Control & Documentation
Biological Activity

Sontuzumab (AS1402) is a humanised IgG1κ MUC1 specific monoclonal antibody. Sontuzumab binds the extracellular MUC1 peptide sequence PDTR with a Kd of ~1 nM. Sontuzumab can be used for the research of breast cancer.

Chemical Information
CAS Number 372075-37-1
Storage Please store the product under the recommended conditions in the Certificate of Analysis.
References

[1] Nuhad K Ibrahim, et al. Clin Cancer Res. Randomized phase II trial of letrozole plus anti-MUC1 antibody AS1402 in hormone receptor-positive locally advanced or metastatic breast cancer

[2] B Royer, et al. Br J Cancer. Population pharmacokinetics of the humanised monoclonal antibody, HuHMFG1 (AS1402), derived from a phase I study on breast cancer

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Keywords: Sontuzumab, AS1402; huHMFG-1 supplier, inhibitors, activators

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