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Somatostatin, also known as growth hormone-inhibiting hormone, is a naturally-occurring peptide hormone of 14 or 28 amino acid residues. Somatostatin is secreted by the D cells of the islets to inhibit the release of insulin and glucagon, and is also generated in the hypothalamus, where it inhibits the release of growth hormone and thyroid-stimulating hormones from the anterior pituitary.
Sequence: H-Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH (Disulfide bridge: Cys3-Cys14)
| Molecular Weight | 1637.88 |
| CAS Number | 51110-01-1 |
| Solubility (25°C) | Water 50 mg/mL |
| Storage | -20°C, sealed |
| Related Somatostatin Receptor Products |
|---|
| Pasireotide
Pasireotide is a somatostatin analog with a 40-fold increased affinity to somatostatin receptor 5 compared to other somatostatin analogs. |
| Octreotide Acetate
Octreotide acetate(SMS 201995 acetate) is a long-acting octapeptide with pharmacologic actions mimicking those of the natural hormone somatostatin. |
| Cyclosomatostatin acetate
Cyclosomatostatin acetate is a potent somatostatin (SST) receptor antagonist. Cyclosomatostatin acetate can inhibit somatostatin receptor type 1 (SSTR1) signaling and decreases cell proliferation, ALDH+ cell population size and sphere-formation in colorectal cancer (CRC) cells. |
| FK962
FK962 is an enhancer of somatostatin release, exerts cognitive-enhancing actions. |
| Lanreotide
Lanreotide is a somatostatin analogue, acts as an inhibitor of growth hormone (GH). |
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