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SM16 is a ALK5/ALK4 kinase inhibitor with Kis of 10 and 1.5 nM, respectively. SM16 penetrates tumor cells in vivo, suppressing tumor phosphorylated Smad2/3 levels for at least 3 h following treatment of tumor-bearing mice with a single i.p. bolus of 20 mg/kg SM16.
| Molecular Weight | 430.5 |
| Formula | C25H26N4O3 |
| CAS Number | 614749-78-9 |
| Solubility (25°C) | DMSO ≥ 55 mg/mL |
| Storage |
Powder -20°C 3 years ; 4°C 2 years In solvent -80°C 6 months ; -20°C 1 month |
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All AbMole products are for research use only, cannot be used for human consumption or veterinary use. We do not provide products or services to individuals. Please comply with the intended use and do not use AbMole products for any other purpose.
Products are for research use only. Not for human use. We do not sell to patients.
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