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SLIGRL-NH2

Cat. No. M10235

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SLIGRL-NH2 Structure
Synonym:

Protease-Activated Receptor-2 Activating Peptide

Size Price Availability Quantity
1mg USD 69 In stock
5mg USD 188 In stock
10mg USD 297 In stock
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Quality Control & Documentation
Biological Activity

SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is an agonist of Protease-Activated Receptor-2 (PAR-2). In the endothelium-free aorta preparations, SLIGRL-NH2 causes a concentration-dependent relaxation in preparations only in the presence of PVAT [+PVAT, -ENDO (endothelium)].

Chemical Information
Molecular Weight 656.82
Formula C29H56N10O7
CAS Number 171436-38-7
Solubility (25°C) Water 90 mg/mL
DMSO 80 mg/mL
Storage -20°C, sealed
References

[1] T Akiyama, et al. Neuroscience. Behavioral model of itch, alloknesis, pain and allodynia in the lower hindlimb and correlative responses of lumbar dorsal horn neurons in the mouse

[2] Y Li, et al. Br J Pharmacol. Perivascular adipose tissue-derived relaxing factors: release by peptide agonists via proteinase-activated receptor-2 (PAR2) and non-PAR2 mechanisms

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Keywords: SLIGRL-NH2, Protease-Activated Receptor-2 Activating Peptide supplier, PAR, inhibitors, activators

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