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SKLB4771 (FLT3-IN-1)

Cat. No. M20679

All AbMole products are for research use only, cannot be used for human consumption.

SKLB4771 (FLT3-IN-1) Structure

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Quality Control & Documentation
Biological Activity

SKLB4771 is a potent and selective inhibitor of human receptor-type tyrosine-protein kinase FLT3 with IC50 of 10 nM.

Chemical Information
Molecular Weight 537.66
Formula C25H27N7O3S2
CAS Number 1370256-78-2
Solubility (25°C) DMSO 50 mg/mL
Storage Powder          -20°C   3 years ;  4°C   2 years
In solvent       -80°C   6 months ;  -20°C   1 month
References

[1] Heng-Xiu Yan, et al. Immunol Res. Accumulation of FLT3(+) CD11c (+) dendritic cells in psoriatic lesions and the anti-psoriatic effect of a selective FLT3 inhibitor

[2] Wei-Wei Li, et al. J Med Chem. Discovery of the novel potent and selective FLT3 inhibitor 1-{5-[7-(3- morpholinopropoxy)quinazolin-4-ylthio]-[1,3,4]thiadiazol-2-yl}-3-p-tolylurea and its anti-acute myeloid leukemia (AML) activities in vitro and in vivo

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  Catalog
Abmole Inhibitor Catalog




Keywords: SKLB4771 (FLT3-IN-1) supplier, FLT3, inhibitors, activators

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